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Fluorescent Sensors of Tyrosine Phosphorylation

Detailed Technology Description: The invention is a novel means for the fluorescent detectionof tyrosine activity. A phosphotyrosine is used to mimic a glutamic acidresidue, Unlike previous methods, this approach combines a genetic encodabilitywith the exhibition of large fluorescence changes upon phosphorylation.Moreover, this approach is applicable to different kinases and phosphotasesthrough modification of the recognition sequence.

Countries: United States

Application No.: Patent Pending

*Abstract: None

*Inquiry: DeniseM. BierleinUniversity of DelawareOffice of Economic Innovation and PartnershipsLicensing AnalystTelephone: (302) 831-4005Email: deniseb@udel.edu

*IP Issue Date: None

*IP Type: Utility

Country/Region: USA

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