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Bioactive Peptide for Cell Adhesion
Detailed Technology Description
The invention is directed to a polypeptide derived fromdomain IV of the extracellular matrix protein perlecan that can selectivelyadhere cells, nucleic acids encoding the inventive polypeptide, vectorscomprising the nucleic acids, devices comprising a scaffold coated with theinventive polypeptide, and methods of adhering cells to a scaffold using theinventive polypeptide. The peptide had applications to in vitro cellular adhesion, including but not limited to:Cell cultureMaterials coatingDevice surface property manipulation Fig. Photograph of 10T1/2 cells plated on plastic coated with the polypeptide of SEQ ID NO:1
Countries
United States
Application No.
7,803,905
Country/Region
USA
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