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Extending the Resolution of Microscopes Beyond the Diffraction Limit

Summary

Researchers at Purdue University have developed a novel solution to achieve super resolution by inserting a set of optics between the microscope and camera. The choice of optics is flexible and used to create interference patterns that allow for localization of light sources at resolutions greater than that of the base microscope. This technique could be used to locate and image fluorescently tagged cell organelles or track microscopic fluorescent particles in fluid. Telescopes could also benefit from this technology by increasing their resolution of faint targets.

Technology Benefits

Library of existing MEMS devices Increased productivity Easy to use

Technology Application

Microscopes Telescopes

Detailed Technology Description

Steve WereleyPurdue Microfluidics GroupPurdue Mechanical Engineering

Countries

United States

Application No.

None

Country/Region

USA

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