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Paper Spray Ionization Without Applied Voltage

Summary

Researchers at Purdue University discovered a system configuration that enables Paper Spray to generate ions for analysis without any voltage source (0 voltage Paper Spray). Solvent is supplied to a porous material, interacts with a sample within the porous material, and flows to the tip of the porous material. Given a short distance between the tip of the porous material and the inlet of the mass spectrometer, the solvent (now containing one or more analytes of the sample) flows from the porous material into the inlet of the mass spectrometer. Random charging during the breakup of droplets occurs, generating sample ions, which are analyzed within the mass spectrometer. In that manner, systems of the invention generate and analyze ions of a sample without the application of voltage to the porous material.

Technology Benefits

Paper Spray ionization without applied voltage Favorable for certain applications, for example those involving live subjects

Technology Application

Mass spectrometry Chemical analysis

Detailed Technology Description

R. Graham CooksPurdue ChemistryAston Labs

Countries

United States

Application No.

N/A

Country/Region

USA

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