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Metabolite-Imaging Mass Spectrometry to Guide Brain Surgery

Summary
Purdue University researchers have developed a method for surgeons to define tumor margins quickly during surgery using miniature mass spectrometers or separate ionization techniques. This method overcomes the need for prepping, staining, and evaluation by a pathologist. It is also possible to adapt this method for other types of cancer surgery.
Technology Benefits
Overcomes need for prepping, staining, and evaluation by a pathologistCan be used to determine tumor boundaries
Technology Application
Medical/HealthcareCancer Treatment
Detailed Technology Description
R. Graham CooksPurdue Biomedical EngineeringAston Labs
Countries
United States
Application No.
None
*Abstract

*Background
Currently, one of the main treatments for brain tumors is surgery. Performing a tumor resection within the brain is difficult because it is not easy to distinguish tumor boundaries from healthy brain tissue. Existing imaging techniques do not provide the necessary molecular information to distinguish tumor boundaries. An unclear boundary between a tumor and healthy tissue can lead to inadequate resection if enough of the tumor remains and neurological damage if healthy tissue is removed.
*IP Issue Date
None
*IP Type
Cont-in-Part
*Stage of Development
Process Validation in Lab
*Web Links
Purdue Office of Technology CommercializationPurdueInnovation and EntrepreneurshipR. Graham CooksPurdue Biomedical EngineeringAston Labs
Country/Region
USA

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