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Ion Generation by Electrospray Using Wetted Porous Material

Summary

Purdue University researchers have developed a method that can combine the sample pretreatment and ionization process to reduce the complexity of the device and make it more efficient. This paper method has many benefits that will address the problem of sample introduction in mass analyzers and accelerate the application of miniature spectrometers in situ analysis.

Technology Benefits

Few other things required for in situ analysisBiological samples can be stored in the precut filter papers for monthsFilter paper minimizes matrix effects and enhances the MS signal of chemicals in complex samplePowdered samples can be directly applied to the paper and then analyzed without requiring pretreatmentPaper can be pretreated to contain internal standards that are released at certain points in quantitative analysis

Technology Application

Chemical Analysis

Detailed Technology Description

R. Graham CooksPurdue ChemistryAston Labs

Countries

United States

Application No.

8,937,288

Country/Region

USA

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