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Second Generation Farnesyl Transferase Inhibitors


Summary

Purdue University researchers have developed a strategy for intracellular delivery of the monophosphates of such FT inhibitors, which could provide an effective therapeutic approach.


Technology Benefits

Intracellular delivery of inhibitorsEnables absolute quantification of known compounds and relative quantification of unknown compounds in most cases using a single liquid chromatography-mass spectrometry (LC-MS) run


Technology Application

Cancer TreatmentMedical/HealthcareBiotechnology


Detailed Technology Description

Richard BorchPurdue Medicinal Chemistry and Molecular Pharmacology


Countries

United States


Application No.

8,324,378


Country/Region

USA

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