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Perfusion and Diffusion Mismatch MR Imaging of the Brain with Radial Acquisition (PENUMBRA)

Technology Benefits
Simultaneous acquisition of perfusion- and diffusion-weighted images Improved spatial resolution Improved coverage, especially of large structures such as the spine Improved accuracy of time-based metrics, such as time-to-maximum and time-to-peak Reduction in cortical blooming artifacts that can make determination of cerebral perfusion unreliable Reduces total acquisition time from 10 or more minutes to less than two minutes Spatial resolution and slice location are identical between perfusion and diffusion images, which eliminates the need for a specially-trained technician to manually overlay images
Detailed Technology Description
Improved perfusion- and diffusion-weighted MRI exam for clinical uses, including imaging for ischemic stoke#healthcare #imaging #mri
*Abstract

Northwestern researchers have developed a non-invasive, diagnostic imaging exam which simultaneously acquires perfusion- and diffusion-weighted magnetic resonance (MR) images for patients with acute ischemic stroke. This single, quick exam uses a 3D-based MR pulse sequence with radial gradient trajectories that acquires high resolution images for the entire brain. The exam takes less than two minutes.

*Inventors
Timothy J. Carroll* Sumeeth V. Jonathan Parmede Vakil Yong Jeong
Country/Region
USA

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