Immunotherapy for Treating Age-Related Macular Degeneration
- Technology Benefits
- Effective induction of immune response Therapy at various stages of AMD: etiology or existing condition
- Detailed Technology Description
- New approach targeting drusen accumulation for treatment and prevention of age-related macular degeneration.#ophthalmology #maculardegeneration #therapeutics #smallmolecule
- *Abstract
-
Northwestern researchers have identified compounds for the treatment and prevention of drusen, tiny accumulations of extracellular material build-up in the macula. Deposition of drusen in the macula is a key factor in the etiology of Age-related Macular Degeneration (AMD). The researchers use an immunotherapeutic approach using antibodies to target against intracellular proteins that, when they become extracellular, contribute to the formation of drusen. The antigen/antibody response mechanism removes these proteins from the eye, decreasing the formation of drusen. This offers a novel therapeutic treatment for AMD by modulating the formation of drusen.
- *Inventors
- Arthur Neufeld* Ai Ling Wang
- Country/Region
- USA
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