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F-nucleatum Associated Defensin Inducer (FADI)

Detailed Technology Description: Dr. Aaron Weinberg's lab is focused on immunomodulation of adaptive immune cells by human beta defensins (hBDs), ~4 to 5-kDa cationic, amphipathic peptides with antimicrobial and immunosurveillance pr

*Abstract: Dr. Aaron Weinberg's lab is focused on immunomodulation of adaptive immune cells by human beta defensins (hBDs), ~4 to 5-kDa cationic, amphipathic peptides with antimicrobial and immunosurveillance properties. The research suggests that these innate defense peptides may function not only to protect the host against microbial pathogens at the mucosal barrier, but also to marshall adaptive host immune responses to both prevent and clear infection.

Country/Region: USA

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