Biotech Cancer Detection Diagnostics Gastrointestinal Disease Dental Indication Medical/Health Nanomedicine
- Technology Benefits
- The magnetic nanoplatform:ΓÇóIs multi-functional, having capability to carry variety of diagnostic, imaging and therapeutic agentsΓÇóComprises use of cationic liposomes containing magnetic particles (MAG-C) for better tumor micro-vasculatureΓÇóTargets the tumor with a very high specificity as compared to conventional mechanismsΓÇóEnables an effective imaging through a magnetic contrast enhancementΓÇóAllows for a significant decrease in tumor signal intensities as compared to conventional systemsΓÇóEffectively delivers therapeutic agents ΓÇÿon-demandΓÇÖ with tailored release profileΓÇóIs completely biodegradable, having reduced toxicity as compared to conventional systemsΓÇóWould be commercially useful for the following key applications:o Bio-imaging such as MRIo Diagnosticso Cancer therapeuticso Anti-cancer research
- Detailed Technology Description
- None
- *Abstract
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Currently, many drug-delivery systems/approaches have been used to target tumor cells/tissues. Cationic liposomes are one of the most common systems currently used in this regards. However, the existing liposomal delivery systems are associated with many possible limitations such as poor, non-uniform and heterogeneous accumulation, as well as reduced stability and circulation time. This invention discloses a novel magnetic nanoparticle construct for various theranostic and multi-modal imaging applications
- *Principal Investigator
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Name: Robert Campbell
Department:
Name: Srinivas Sridhar
Department:
- Country/Region
- USA
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