Modified Sleeping Beauty Transposon Gene Transfer System
- Detailed Technology Description
- None
- *Abstract
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This synthetic transposon system uses modified Sleeping Beauty vectors for a variety of functional genomic applications. The vectors can be used to identify and characterize genomic coding sequences and localize gene expression. This system can also be used to identify, isolate, and characterize transcriptional regulatory sequences. SB vector modification allows for gene transfer and long-term expression of genes in chromosomes. This SB system could be useful for therapeutic gene therapy.
- *Principal Investigator
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Name: Perry Hackett, PhD
Department:
- Country/Region
- USA
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