Cell Cryopreservation for Lymphocytes
- Detailed Technology Description
- None
- *Abstract
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A method has been developed that utilizes cryopreservative agents for improving the survivability of hematopoietic cells when frozen. Using a balanced electrolyte solution with an arabinogalactan equivalent, a high-survival rate of hematopoietic cells is maintained. It contains a much smaller concentration of glycerol compared to other methods and does not use DMSO, thus decreasing cell loss due to osmotic stress and DMSO toxicity. This technique will increase effectiveness of cell therapeutics by increasing cell viability following cryopreservation. Overall, this cell cryopreservation method will enhance lymphocyte treatments for tumors, especially following bone marrow transplants, as well as treatments for viral infections.
- *Principal Investigator
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Name: Allison Hubel, PhD, Professor
Department: Department of Mechanical Engineering, College of Science and Engineering
- Country/Region
- USA
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