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Novel Cell Penetrating Peptides

Technology Benefits: The cell penetrating peptides (CPPs) identified in this technology are of shorter length and simpler structure than most known CPPs. Due to these characteristics, these CPPs are more cost effective to produce and are effective in penetrating cell membranes to deliver cargo.

Technology Application: CPPs are an effective way to deliver molecules and agents to the interior of a cell. These peptides may be used in therapeutic applications and demonstrate antimicrobial properties.

Detailed Technology Description: None

Supplementary Information: Inventor: Zheng, Yi | Williams, David A.
Priority Number: US7915384B2
IPC Current: C07K001400 | A01N003718 | C07K001447 | C12N000914
US Class: 530350 | 514002
Assignee Applicant: Children's Hospital Medical Center,Cincinnati
Title: Chimeric peptides for the regulation of GTPases
Usefulness: Chimeric peptides for the regulation of GTPases
Summary: The chimeric polypeptide and compositions are useful for treating a disease related to up-regulation of GTPase activity, e.g. cancer (claimed).

Industry: Disease Diagnostic/Treatment

Sub Category: Cancer/Tumor

*Abstract: Molecules useful in the treatment of disease in humans and animals. This technology identifies several highly potent cell penetrating peptides (CPPs) that are soluble and nontoxic.

*Principal Investigator: Name: William Wimley
Department:

Country/Region: USA

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