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Human Leukocyte Antigen "HLA"

Technology Benefits

HLA testing is particularly useful in bone-marrow transplantpatients both prior to transplant for matching purposes and aftertransplant to monitor rejection.

Technology Application

Companies interested in diagnostic testing, molecular analysis,and tissue typing applications especially in the field oftransplantation.

Detailed Technology Description

Methods for HLA typing HLA Ia, Ib, Ic, II, III, IIIb.HLA locus is selected from HLA A, B, C, DP, DQ and DR.Composition of matter and testing methodologies.HLA testing is particularly useful in bone-marrow transplantpatients both prior to transplant for matching purposes and aftertransplant to monitor rejection.HLA testing and crossmatching is used in both solid organtransplants and bone marrow transplants. In 2002 in the US80,000 patients needed solid organ transplants. Approximately5,000,000 patients are enrolled in the National Marrow DonorProgram.Issued US patents:5,468,611** 6,194,147 5,545,526 6,503,707 5,702,885**Patent is exclusively licensed. Sub-licenses may be available upon request.

Country/Region

USA

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