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Gene Copy Number Profiling

Detailed Technology Description: None

*Abstract: BackgroundA large number of cancer patients present to their physician with more than one tumor. In some instances the origin of the different tumors in the patient are distinguishable based on standard histological analysis. In other cases it is difficult to identify the tissue of origin of the cancer, or properly stage the cancer, if the relationship between the tumors in a patient is not properly ascertained. Are the tumors independent primaries? Are the tumors a primary and a metastasis? The answers to these questions are not always knowable based on standard clinical practice.TechnologyCopy number profile analysis is used to determine whether two or more separate tumors in a single individual are derived from a common source. Applications1. Determines whether two separate tumor samples are derived from the same source2. Staging and classification of cancer in a patientAdvantages1. Allows a custom treatment regimen for the patient

*Principal Investigator: Name: Julie Deloia
Department: Department of Human Science

Name: Esther Elishaev
Department: Med-Pathology

Name: Alfred Guirguis
Department:

Country/Region: USA

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