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MODIFIED IMMUNOGENIC PEPTIDE AGAINST STREPTOCOCCUS A


Summary

An immunogenic peptide for prevention and treatment of group A streptococcus streptococcus-associated diseases and conditions


Technology Benefits

Vaccine to prevent group A streptococci infection


Technology Application

Vaccine - disease prevention


Detailed Technology Description

The present inventors have discovered that the immunogenicity of a p145 peptide can be substantially increased by targeted modification of the amino acid sequence of p145. A single immunization with the modified p145 peptide, rather than multiple immunizations, can protect against group A streptococcus infection even by hypervirulent strains such as the CovR/S mutant strain.


Type of Cooperation

Licensing


Application Date

23/08/2017 00:00:00


Application No.

2019439


Country/Region

Netherlands

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