Media.Player

Managing Health by Balancing Gut Microbiota

Summary

Three phytosynbiotic formulations have been developed:Anti-metabolic syndrome formulation (AMF). The AMF is formulated by fermenting Momordica charantia and Moringa oleifera with a consortium of enriched lactobacilli. The AMF has been tested on diabetic patients in an overseas hospital. The results are as follow:AMF reduces blood glucose levels from diabetic to normal state within a month and performs as effective as insulinAMF lowers LDL cholesterol levels while boosting HDL cholesterol levelsAMF restores liver enzyme levels (ALT and AST) to normalBrain development formulation (BDF). The BDF is formulated by fermenting Rhodiola rosea, Cistanche deserticola and Prunus dulcis using a consortium of enriched lactobacilli. The plants are chosen for their known properties to increase neurotransmitters such as dopamine, serotonin, acetylcholine and others.Hormonal balancing formulation (HBF). The HBF is formulated by using a consortium of enriched lactobacilli to co-ferment Brassica oleracea, Apium graveolens var. dulce, Lentinula edodes and Laminariales. The plants are selected for their known abilities to provide large amounts of vital antioxidants with anti-inflammatory and anti-cancer properties.All three formulations improve gut health and boost general immunity. 

Technology Benefits

The phytosynbiotic technology benefits customers in many ways:AMF may help patients who had contacted metabolic syndrome and people who have tendencies to contact metabolic syndrome to better manage their glucose and cholesterol levels.BDF may help people with neurodevelopmental disorders to better concentrate and focus, enhance memory, boost energy levels, and reduce depression & anxiety.HBF may help cancer patients to mitigate the side effects of chemotherapy and radiotherapy treatment, and promote speedier recovery. It may also help mitigate allergic reactions, hence improving the quality of life of people suffering from allergies.

Technology Application

This technology can be used to develop health supplements and functional food ingredients to complement conventional medicine and therapies.AMF can be used to provide support for:Patients who have already contacted metabolic syndrome including diabetes & hypercholesterolemia. AMF may be used as an orally administered adjuvant to complement anti-diabetic and/or anti-cholesterol medication.People showing tendencies for contacting metabolic syndrome including pre-diabetes or pre-high cholesterol. AMF may be used as a preventative health supplement to maintain healthy levels of glucose and cholesterol.BDF can be used to provide support for:Patients who are suffering from neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD), autism spectrum disorders (ASD) and dementia.People who have needs to improve mental concentration and raise energy levels.HBF can be used to provide support for:Patients who are seeking faster recovery after undergoing major medical interventions such as chemotherapy and radiotherapy. HBF may be used to reduce side effects of such therapies.Patients who are suffering from allergic reactions such as food intolerance, eczema and sinusitis.

Detailed Technology Description

This technology is:Condition-specific. A variety of specific health conditions can be addressed by different probiotic-plant combinations.Robust. Probiotics are protected to ensure their survival during passage through the digestive tract.Safe: Phytosynbiotic are food grade and of GRAS status.Repeatable: The upscaling process to produce co-fermented complex microbial communities with pre-defined ratios, is consistent and repeatable.Controllable. Both culturable and non-culturable components of the phytosynbiotic formulations can be quality controlled in a quantitative manner.Scaleable. The production facility is modular with small footprint.The precise mode of action is still unknown. However, preliminary evidence suggests that phytosynbiotics are able to rebalance gut microbiota and help shift the hosts from a diseased to healthy state. 

Application Date

27-Jul-2015

ID No.

TO17466

Country/Region

Singapore