Method for measuring free Thrombin Activity
- Summary
- Current methods depend on fluorogenic substrates that are unable to distinguish free thrombin and the new invention allows thrombin not bound to A2M to be distinguished from thrombin bound to A2M.
现行检测方法主要使用荧光底物，但荧光底物不能辨别游离凝血酶，新的干预方法能区别与A2M结合的凝血酶，以及与A2M结合的凝血酶。
This innovative technology does not rely on such assumptions but on direct measurement of thrombin not bound to A2M. As a result, thrombin generation can be quantified directly in plasma or blood over time, in vitro without having to extract the extraneous measurement of thrombin-A2M.
本创新技术的基础并非该假设，而是直接测量不与A2M结合的凝血酶。这种技术将在一段时间后直接在血浆或血液中体外量化凝血酶生成情况，不需要提取凝血酶-A2M的外部测量值。
Simple, streamlined assay that eliminates the complexity and imprecision of current thrombin measurements.
是一种简单、改进的测定方法，解决了现有凝血酶检测方法复杂程度高、结果不准确的缺点。
Potential to become a standard measure of hemorrhagic or prothrombotic tendency, as well as an anticoagulant assessment, for routine clinical practice.
有望成为日常临床实践中检测出血或凝血倾向以及评价抗凝剂的标准方法。
Could extend method to distinguish between free and bound forms of any enzyme, both within and beyond enzymes of coagulation.
可以扩展凝血酶及其他酶的游离酶和结合酶区分方法。
This novel invention could be used for diagnostic purposes and for the development of new anticoagulants or bleeding treatments.
本发明可用于诊断，开发新的抗凝血药或出血治疗方法。
- Detailed Technology Description
- Ready for pilot plant test manufacturing
准备进入试验工厂试生产阶段
- Type of Cooperation
- 技术售让
- Coverage Areas
- 生物技术/制药/医疗
- Goods and Services
- 研发机构/实验室
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