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EFFICIENT ISOLATION OF CIMIRACEMATE A, AND METHODS OF USE

Summary
A method for isolating cimiracemate A from a Cimicifuga species is disclosed, comprising the steps of a) providing a sufficient quantity of raw materials from the Cimicifuga species, b) mixing the raw materials from the Cimicifuga species with an aqueous polar solvent at a temperature of about 20 DEG C to about 28 DEG C to obtain a solvent extract comprising cimiracemate A, and c) isolating cimiracemate A from the solvent extract.
Supplementary Information
Patent Number: US8633332B2
Application Number: US13379008A
Inventor: Yang, Lai Hung Cindy | Sy Lau, Allan
Priority Date: 21 Jun 2009
Priority Number: US8633332B2
Application Date: 9 Apr 2012
Publication Date: 21 Jan 2014
IPC Current: C07C006976
US Class: 560061
Assignee Applicant: Purapharm Company Limited
Title: Efficient isolation of cimiracemate A, and methods of use
Usefulness: Efficient isolation of cimiracemate A, and methods of use
Summary: The cimiracemate A is useful: as a therapeutic composition, a dietary supplement, a bioactive chemical marker and standard for various species of Cimicifuga . The cimiracemate A is useful for treating malaise, malaria, rheumatism, abnormal kidney function, sore throat, menstrual irregularities, diseases associated with childbirth, fever, headache pain, and chills. The cimiracemate A is useful to suppress lipopolysaccharide-induced TNFα in human macrophages, and as a reactive oxygen species scavenger. No biological data given.
Novelty: Isolating cimiracemate A from Cimicifuga species, comprises providing raw material of Cimicifuga species, mixing the raw material of Cimicifuga species with aqueous polar solvent and isolating cimiracemate A from obtained solvent extract
Industry
Biomedical
Sub Category
Pharmaceuticals
Application No.
US13379008A
Country/Region
Hong Kong

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