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Reagents for detection of hypochlorous acid

Summary
Provided herein are compounds or hypochlorous acid probes which can be used as reagents for measuring, detecting and/or screening, directly or indirectly, hypochlorous acid or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of hypochlorous acid or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the hypochlorous acid probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening hypochlorous acid or compounds that can increase or decrease, directly or indirectly, the level of hypochlorous acid or hypochlorite in chemical and biological samples.
Supplementary Information
Inventor: YANG DAN | SUN ZHEN-NING | CHEN YAN | LIU FENGQIN
Priority Number: AT526333T
IPC Current: C07F000502 | G01N003100
Assignee Applicant: Versitech Ltd
Title: REAGENTIEN ZUM NACHWEIS VON HYPOCHLORIGER SÄURE
Usefulness: REAGENTIEN ZUM NACHWEIS VON HYPOCHLORIGER SÄURE
Industry
Chemical/Material
Sub Category
Chemical/Material Application
Application No.
CN200880014862A
Country/Region
Hong Kong

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