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METHOD FOR PRODUCING MUTANT CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN (CFTR)

Summary

PROBLEM TO BE SOLVED: To provide a technique for screening and detection of a cystic fibrosis(CF) carrier, CF diagnosis and therapy. SOLUTION: The CF protein gene usable for screening and detection of the carrier, CF diagnosis and therapy is cloned, isolated and purified.

Supplementary Information

Inventor: LAP-CHEE TSUI | RIORDAN JOHN R | COLLINS FRANCIS S | ROMMENS JOHANNA M | IANNUZZI MICHAEL C | KEREM BAT-SHEVA | DRUMM MITCHELL L | BUCHWALD MANUEL
Priority Number: JP2002355088A
IPC Current: A01K0067027 | A61K003800 | A61K004800 | A61P000118 | A61P000300 | A61P000500 | A61P001100 | A61P004300 | C07H002104 | C07K000122 | C07K001400 | C07K001447 | C07K001600 | C07K001618 | C07K001628 | C12N000115 | C12N000119 | C12N000121 | C12N000510 | C12N001509 | C12N001512 | C12N001585 | C12P002102 | C12P002108 | C12Q000168 | G01N003353 | G01N0033566 | G01N0033577
Assignee Applicant: HSC Research Development Corporation,Toronto | The Board of Regents Acting for and on Behalf of the Unversity of Michigan
Title: METHOD FOR PRODUCING MUTANT CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN (CFTR) | The manufacturing method of variation|mutation cystic fibrosis transmembrane conductance regulating protein (CFTR)
Usefulness: METHOD FOR PRODUCING MUTANT CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN (CFTR) | The manufacturing method of variation|mutation cystic fibrosis transmembrane conductance regulating protein (CFTR)
Summary: USE The CF gene and its gene prod., nucleic acid probes and antibodies to the gene prod. can be used for screening for and detection of CF carriers, CF diagnosis and prenatal CF screening and diagnosis. The gene prod. and gene therapy can be used for CF therapy. The prods. can also be used to develop improved methods of treatment and to study the disease.
Novelty: Cystic fibrosis gene used to produce prods. for screening, detection, diagnosis, therapy and studying cystic fibrosis

Industry

Biomedical

Sub Group

DNA/Gene Engineering

Country/Region

Hong Kong

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