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A Novel RING HC Domain Gene Confers Disease Resistance in Plants

Summary

A novel RING HC domain gene was cloned from the monocot plant rice. Expression of this gene in the dicot plant Arabidopsis thaliana enhances disease resistance and elevates expression of defense marker genes. Overexpression of this gene in rice also leads to induction of defense marker genes in rice. The successful protection effect of a monocot gene in a dicot plant indicates its capability of broad spectrum resistance. No obvious negative effects of the transgene (such as program cell death) were exhibited by the transgenic plants. The invention can be applied to enhance broad spectrum disease resistance in crops.

Supplementary Information

Inventor: Lam, Hon-Ming | Sun, Sai Ming Samuel
Priority Number: US7994393B2
IPC Current: A01H000500 | C12N001509 | C12N001582
US Class: 800279 | 4353201 | 435418 | 435419 | 435468 | 800278 | 800298
Assignee Applicant: The Chinese University of Hong Kong
Title: Method to improve plant resistance to infections
Usefulness: Method to improve plant resistance to infections
Summary: The recombinant expression system, antibodies, proteins, and methods are useful for conferring an enhanced ability to resist infections or wounding on a plant; for preparing a protein that has the amino acid sequence given in the specification or variants that are at least 95% identical to the amino acid sequence and that confers on plants resistance to trauma; and for identifying a compound or combination of compounds that modulate the ability of plants to resist infections or wounding (all claimed).
Novelty: New recombinant expression system, comprises a nucleotide sequence encoding a protein, useful for conferring an enhanced ability to resist infections or wounding on a plant

Industry

Agriculture

Sub Category

Plant

Application No.

07/SCI/259

Others

Inventor(s): Professor Lam Hon Ming, Department of Biology

Patent Status:  US Patent Pending

Country/Region

Hong Kong