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Superparamagnetic Iron-oxide Particles and Polymer based Chemoembolisation System for Trans-catheter Targeted Delivery, Selective Retention, Magnetic Targeting, and Magnetic Resonance Imaging Contrast

Summary: Multi-functional superparamagnetic iron oxide nanomaterials and biocompatible polymer based chemoembolisation systems were constructed. These systems allow trans-catheter targeted delivery, selective retention in tumor tissue, magnetic targeting, and magnetic resonance visualization. The tumor can be deprived of blood supply due to the embolisation. The anti-cancer drug can be slowly released in tumor site, or the anti-cancer drug nanomaterials can be up-taken by tumor cells and causing enhanced cytotoxicity to tumor cells.

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Application No.: 09/MED/342/ITF

Others: Inventor(s): Professor Yixiang WANG, Department of Diagnostic Radiology and Organ Imaging

Patent Status: US Patent Pending Licensing Status: Available for licensing

Country/Region: Hong Kong

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