Vitamin-C Surgical Irrigation Solution for Tendon and Ligament Injuries
- Summary
- Tendon and ligament injuries are very common sporting and occupational injuries. Surgical repair provides a mechanically stable micro-environment for the tendons or ligaments to heal, but the healing outcomes are always compromised by the low innate healing capacity. Thus it is important to study potential treatments to promote the innate healing capacity. We discovered that surgical irrigation with vitamin C solution may be able to improve healing in animal models. Conventional surgical irrigation solution only acts as neutral fluid to cleanse the surgical sites. Limited modifications of surgical irrigation solution have been proposed to reduce infection or bleeding, but there is no investigation to develop irrigation solution with an added value to improve healing outcomes. We propose to develop a new formula of vitamin C supplemented surgical irrigation solution which can promote tendon and ligament healing. Pre-clinical studies in well-established animal models will be used to evaluate the effects of the new irrigation solution, and the results will be used to apply for patents. In the next stage of the product development, clinical trials could be conducted with industrial collaboration.
- Application No.
- 11/MED/402
- Others
- Inventor(s): Professor Kai Ming CHAN, Department of Orthopaedics and Traumatology Licensing Status: Available
- Country/Region
- Hong Kong
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