AsiaIPEX is a one-stop-shop for players in the IP industry, facilitating IP trade and connection to the IP world. Whether you are a patent owner interested in selling your IP, or a manufacturer looking to buy technologies to upgrade your operation, you will find the portal a useful resource.

Back to search results

VisuVivo

Summary

A proliferation marker to visualise cell cycle progression in vitro and in vivo with high spatial resolution of the M-phase

Technology Benefits

Visualising proliferating cells in vitro & in vivo
Identification, isolation and characterisation of proliferating cells
Discrimination between cell division and acytokinetic mitosis / endoreplication
Applicable in cell systems containing a mixture of proliferating, differentiated and post-mitotic cells

Technology Application

VisuVivo can aid to gain knowledge about mechanisms of cell proliferation, which could be useful for stem cell biology as well as regenerative medicine and others.

Detailed Technology Description

The invention provides a nucleic acid expression construct encoding a fusion protein comprising a fluorescence reporter protein (like EGFP) and a protein with a wild-type destruction signal (like Anillin). Localised to subcellular structures during cell cycle progression, it presents a fluorescence marker for imaging cell cycle progression in vitro and in vivo.

Type of Cooperation

Licensing

Application Date

15/07/2010 00:00:00

Application No.

US201013383580 20100715

Classes

- international:
A01K67/027; C12N15/63; C12Q1/02; G01N33/50; G01N33/53
- cooperative:
C07K14/4738; C12N15/63

Others

Patent application

ID No.

2092

Country/Region

Germany

For more information, please click Here