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VisuVivo

总结

A proliferation marker to visualise cell cycle progression in vitro and in vivo with high spatial resolution of the M-phase

技术优势

Visualising proliferating cells in vitro & in vivo
Identification, isolation and characterisation of proliferating cells
Discrimination between cell division and acytokinetic mitosis / endoreplication
Applicable in cell systems containing a mixture of proliferating, differentiated and post-mitotic cells

技术应用

VisuVivo can aid to gain knowledge about mechanisms of cell proliferation, which could be useful for stem cell biology as well as regenerative medicine and others.

详细技术说明

The invention provides a nucleic acid expression construct encoding a fusion protein comprising a fluorescence reporter protein (like EGFP) and a protein with a wild-type destruction signal (like Anillin). Localised to subcellular structures during cell cycle progression, it presents a fluorescence marker for imaging cell cycle progression in vitro and in vivo.

合作类型

Licensing

申请日期

15/07/2010 00:00:00

申请号码

US201013383580 20100715

分类

- international:
A01K67/027; C12N15/63; C12Q1/02; G01N33/50; G01N33/53
- cooperative:
C07K14/4738; C12N15/63

其他

Patent application

ID号码

2092

国家/地区

德国