AsiaIPEX is a one-stop-shop for players in the IP industry, facilitating IP trade and connection to the IP world. Whether you are a patent owner interested in selling your IP, or a manufacturer looking to buy technologies to upgrade your operation, you will find the portal a useful resource.

Back to search results

New Resins for Serial Block-Face Scanning Electron Microscopy

Detailed Technology Description: University researchers have developed new resins to immobilize tissue samples in Serial Block-face Scanning Electron Microscopy (SBFSEM). The invention has been demonstrated to lead to dramatic improvements in image contrast and resolution for SBFSEM.

Application No.: 20160163505

Others: Tech ID/UC Case
24220/2014-007-0

Related Cases
2014-007-0

*Abstract: The advent of serial block-face scanning electron microscopy (SBFSEM) promises to revolutionize histology and neuroanatomical research by allowing the 3-dimensional reconstruction of relatively large regions of tissue and cell arrays at near nanometer-scale resolution. In SBFSEM, successive slices are removed from the targeted tissue and an electron beam is scanned over the remaining block-face to produce electron backscatter images. A principal limitation of this approach is that the resolution obtainable using backscatter electron imaging at low accelerating voltage is modest compared to traditional transmission electron microscopy.

*IP Issue Date: Jun 9, 2016

*Principal Investigator: Name: James Bouwer
Department:

Name: Eric Bushong
Department:

Name: Thomas Deerinck
Department:

Name: Mark Ellisman
Department:

Name: Donald Johnson
Department:

Name: Ranjan Ramachandra
Department:

Name: Jay Siegel
Department:

Country/Region: USA

For more information, please click Here