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Compositions and Methods for Treating Mammary Tumors
Technology Benefits
Potential therapeutic for anti-estrogen resistant cancersCan restore sensitivity to Tamoxifen and FulvestrantCan be used alone or in conjunction with Tamoxifen
Detailed Technology Description
Resistance to anti-estrogenic therapies remains as a very significant problem in the treatment of breast cancer. The present invention describes small molecules for the treatment or prevention of breast cancer. These compounds are effective against anti-estrogen resistant cells, and most remarkably, restore the sensitivity of Tamoxifen and Fulvestrant-resistant cells to Tamoxifen and Fulvestrant.
Country/Region
USA
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