Compositions and Methods for Treating Mammary Tumors
- 技術優勢
- Potential therapeutic for anti-estrogen resistant cancersCan restore sensitivity to Tamoxifen and FulvestrantCan be used alone or in conjunction with Tamoxifen
- 詳細技術說明
- Resistance to anti-estrogenic therapies remains as a very significant problem in the treatment of breast cancer. The present invention describes small molecules for the treatment or prevention of breast cancer. These compounds are effective against anti-estrogen resistant cells, and most remarkably, restore the sensitivity of Tamoxifen and Fulvestrant-resistant cells to Tamoxifen and Fulvestrant.
- *Abstract
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None
- *Publications
- Manuscript in preparation.
- *Stage of Development
- Researchers have identified compounds that inhibit ER-α activity in multiple cell lines. Mechanism of action studies have been completed.
- 國家/地區
- 美國
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