This invention offered an in vivo mouse model that captures the disease state and has greater relevance to the disorder.This animal line has normal life span, in contrast to the lethal phenotype observed in the homozygous Sco2 KO mice.Mice, compared with other animal models, are relatively economica.....
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Conditional deletion allows the researcher to breed with mouse lines that have the recombinase under pharmacological and/or cell-type or tissue specific promoters for temporal and spatial deletion of the microRNA cluster to determine when and where this cluster is of importance.Can be crossed with m.....
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Lead Inventors: Drew Tortoriello, MD.Problem or Unmet Need:While surgical and medical treatments are available to treat endometriosis, none of the available options provides optimal long-term solution. Specifically, hormonal therapy is slow at providing substantial pain relief and is associated with.....
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