This invention provides an engineered degradation-resistant HOXB4 protein, materials and methods to produce it, and methods to use this recombinant protein for the ex vivo expansion of hematopoietic stem cells.
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Reduces chronic conditions assocated with menopause with an improved safety profile
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Intravenous administration of daunorubicin is an FDA-approved drug for the treatment of oncologic malignanciesDaunorubicin induces cell death and suppresses pulmonary artery constriction in a hypoxia-induced animal model of pulmonary hypertensionDaunorubicin mediated suppression of pulmonary artery .....
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