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4(1H)-Quinolones Having Anti-Malarial Activity with Reduced Chemical Resistance
技術優勢
Potent anti-malarial activityImproved chemical resistance against multi-drug resistant (MDR) parasitesActs on both MDR parasites and drug susceptible anti-malarial strains equally well
技術應用
antimalarial drugs
詳細技術說明
This invention promises a great approach to treat those affected with malaria. The compound possesses a potent EC50 against multidrug resistant malarial strains W2 (chloroquine and pyrimethamine resistant) and TM90-C2B (chloroquine, mefloquine, pyrimethamine, and atovaquone resistant). This compound also exhibits signs of reduced chemical resistance.
國家/地區
美國
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