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4(1H)-Quinolones Having Anti-Malarial Activity with Reduced Chemical Resistance
技术优势
Potent anti-malarial activityImproved chemical resistance against multi-drug resistant (MDR) parasitesActs on both MDR parasites and drug susceptible anti-malarial strains equally well
技术应用
antimalarial drugs
详细技术说明
This invention promises a great approach to treat those affected with malaria. The compound possesses a potent EC50 against multidrug resistant malarial strains W2 (chloroquine and pyrimethamine resistant) and TM90-C2B (chloroquine, mefloquine, pyrimethamine, and atovaquone resistant). This compound also exhibits signs of reduced chemical resistance.
国家/地区
美国
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