Oligosaccharide to Prevent Necrotizing Enterocolitis
A researcher at UC San Diego has identified a bioactive human milk oligosaccharide lacking from infant formula that inhibit key events in necrotizing enterocolitis pathogenesis.
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State Of Development Acquired in vivo data showing that human milk oligosaccharides (HMO) significantly reduce NEC in an animal disease model. Specifically, rats receiving formula without a specific HMO developed NEC with an average pathology score of 1.98. The pathology score was significantly reduced when supplemented with HMO in the range of 0.1 and 10 mg/mL, resembling the HMO concentration in rat and human milk, respectively. None of the rats that received HMO had a pathology score that was higher than the average score of rats that received formula without HMO. Breast-fed pups were not significantly different from rats that received HMO with their formula. Related Materials Tech ID/UC Case 21416/2011-192-0 Related Cases 2011-192-0
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