High Resolution, Diagnostic Imaging of Fat Composition and Regional Location
Totally automated image reconstruction and data analysis.Requires only one breath-hold scan added to a standard MR examination.Yields diagnostic information that cannot be derived from other non-invasive means.
This technology can improve diagnostic utility for patients of diverse diseases that are characterized by specific types and locations of fat deposits. Such diseases include cancer, diabetes, and liver disease.
Commonly employed MRI techniques for separating water and fat exploit differences in the precession frequency of protons in fat and water. UC researchers have simplified and improved analysis and data processing by identifying three most-relevant parameters that can be used to qualitatively and quantitatively image fat. By reducing the complexity of an MRI-generated fat spectrum, one is able to significantly improve the diagnostic utility of a scan with minimal effect on the scan time.
Patent Number: WO2012061839A3
Application Number: WO2011US59660A
Inventor: BYDDER, Mark | HAMILTON, Gavin | MIDDLETON, Michael | SIRLIN, Claude
Priority Date: 5 Nov 2010
Priority Number: WO2012061839A3
Application Date: 7 Nov 2011
Publication Date: 2 Aug 2012
IPC Current: A61B0005055 | G06F001900
Assignee Applicant: The Regents of the University of California
Title: MRI-BASED FAT DOUBLE BOND MAPPING | MAPPAGE DE LIAISONS DOUBLES DE GRAISSE BASÉ SUR L'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE
Usefulness: MRI-BASED FAT DOUBLE BOND MAPPING | MAPPAGE DE LIAISONS DOUBLES DE GRAISSE BASÉ SUR L'IMAGERIE PAR RÉSONANCE MAGNÉTIQUE
Summary: MRI method for producing fat characterization profile from acquired MRI image used in diagnosis and treatment plans for disease such as cancer to evaluate tumors/lesions and decide if malignant or benign, liver disease to differential between simple steatosis and steaohepatities, and diabetes to detect brown fat that is indicator for predisposition to develop diabetes.
Novelty: MRI method for producing fat characterization profile from acquired MRI image to determine type and saturation level of fat involves determining fat characterization parameters based on acquired magnetic resonance data
生物醫學
醫學影像
9759794
State Of Development In vitro validation is complete. Studies with human subjects are underway: the type and quantity of fat in the abdomen are measured with 5 mm resolution in a 24 second scan. Intellectual Property Info Pending patents available under confidentiality; worldwide, non-exclusive IP rights and copyright (software) available. Related Materials Tech ID/UC Case 21265/2011-012-0 Related Cases 2011-012-0, 2008-830-1, 2010-814-1
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