Exosomen
Use of exosomes in the prevention and therapy of diseases associated with acute inflammatory processes.
Selected MSC exosome preparations exert immune suppressive functions
New treatment option in diseases associated with acute inflammatory processes
Well tolerated
MSC exosome administration of selected preparations are promising new treatment option in the prevention and therapy of diseases associated with acute inflammatory processes, such as GvHD, stroke, heart-attack and neonatal damages of the brain and lungs.
Exosomes are nano-sized, secreted cell organelles that are released by a huge variety of different cell species, including mesenchymal stem cells (MSCs). Containing a combination of lipids and proteins as well as RNAs, exosomes participate in intercellular communication processes.
Due to the wide range of molecules they enclose and their cell type specific assembly, these small membrane vesicles get more and more in the focus of diagnosis, drug delivery and clinical applications.
Licensing
18/07/2013 00:00:00
US201314414843 20130718
- international:
A61K35/28; A61K38/18; A61K38/19; A61K38/20; A61K38/21; A61K9/00
- cooperative:
A61K35/28; A61K38/17; A61K38/1709; A61K38/1841; A61K38/19; A61K38/2053; A61K38/2066; A61K38/217; A61K9/0019
Patent application
3321
德国
