Antibacterial Agents Against Methicilin- and Vancomycin-Resistant Bacteria
Researchers at Purdue University have identified compounds with potent antibacterial activities. The most potent compounds inhibited growth of various-resistant Gram-positive bacterial pathogens. Some compounds were active against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus (VISA and VRSA respectively), and vancomycin-resistant Enterococcus faecalis (VRE). Through resistance generation experiments it was revealed that MRSA could not develop resistance to one of these compounds.
Compounds can kill methicillin and vancomycin-resistant bacteriaNo resistance from MRSAPotent activity against drug-resistant Gram-positive pathogens
Pharmaceuticals/biotech companiesAnimal medicineBacterial burden in skin wound infections
Herman SintimSintim Research GroupPurdue Chemistry
United States
None
美国
