Multiplexed Micro-columns for Improved Aptamer Selection

A new approach was developed for identifying aptamers for multiple target molecules simultaneously, offering a major improvement over typical SELEX methods which are limited to one or a few protein targets.

• Patent application: WO/2013/170256

• Latulippe, D. R.; Szeto, K.; Ozer,A.; Duarte, F. M.; Kelly, C. V.; Pagano, J. M.; White, B. S.; Shalloway, D.;Lis, J. T.; Craighead, H. G., “Multiplexedmicrocolumn-based process for efficient selection of RNA aptamers," Analytical Chemistry 2013

• Latulippe, D. R.; Szeto, K.; Ozer, A.; Pagano, J.;Kelly, C., Lis, J.T.; Craighead, H.G., “Advancedcharacterization of a novel multitarget microscale fluidic device for theselection of RNA aptamers,” 244th ACSNational Meeting & Exposition, Pub. 188 (2012)

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