亚洲知识产权资讯网为知识产权业界提供一个一站式网上交易平台，协助业界发掘知识产权贸易商机，并与环球知识产权业界建立联系。无论你是知识产权拥有者正在出售您的知识产权，或是制造商需要购买技术以提高操作效能，又或是知识产权配套服务供应商，你将会从本网站发掘到有用的知识产权贸易资讯。

返回搜索结果

Chemically Amplified Response Strategies for Medical Sciences

技术优势

Potential advantages from molecularly engineering linear dual-response mechanisms into the backbone of polymeric nanoparticles include enhanced stability and prolonged shelf life, while also increasing the response sensitivity and efficacy of targeted delivery to diseased environments. In addition, this polymeric nano-carrier technology may reduce overall toxicity by decomposing into easily excretable fragments. This technology is designed to be versatile where the triggering group can be sensitive to a number of wavelengths.

详细技术说明

Researchers from UC San Diego have designed a new light-sensitive degradable polymer containing a quinone-methide, self-immolative moiety, which can be triggered to degrade through multiple light-sensitive groups. Nanoparticles formulated from this polymer are capable of releasing their molecule payload upon irradiation by UV and NIR light. The details of this technology are published in the patent application (2011/038117).

附加资料

Patent Number: US20120259267A1
Application Number: US13496486A
Inventor: Almutairi, Adah | Fomina, Nadezda | Sankaranarayanan, Jagadis
Priority Date: 23 Sep 2009
Priority Number: US20120259267A1
Application Date: 28 Jun 2012
Publication Date: 11 Oct 2012
IPC Current: C07C0049175 | A61K0039395 | A61K005100 | A61M003700 | B01J001908 | C07D031102 | C08F002056
US Class: 604020 | 2504921 | 42400111 | 4241301 | 525284 | 549283 | 568414
Assignee Applicant: The Regents of the University of California
Title: Chemically Amplified Response Strategies for Medical Sciences
Usefulness: Chemically Amplified Response Strategies for Medical Sciences
Summary: For delivering Payload to tissue, where the Payload comprises pharmaceutical agent, stem cell differentiation agents, immunogens, and antibodies (claimed); for amplifying sensitivity to electromagnetic radiation, or light, such as UV light or near infrared light.
Novelty: Composition for delivering Payload such as pharmaceutical agent, stem cell differentiation agents, immunogens and antibodies, to tissue comprises multi-photon responsive element covalently linked to self-immolative backbone subunit