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A Biliverdin-Binding RNA Aptamer for Fluorescent RNAs and a Small RNA Sensor
详细技术说明
University of Delawareresearchers have created a fluorescent RNA sensor, which is capable ofdetecting cognate small RNA with high specificity, across a broad dynamicrange. The researchers have also developed a system for screening geneticallyencoded, endogenous fluorophore, biliverdin (BV). The screening andcharacterization of BV-binding RNA aptamers enables non-invasive deep-tissuemonitoring of RNA in vivo. Thetechnology can also be used for measurement of small RNAs or other smallmolecules that can be detected by an RNA-based sensor.
国家
United States
申请号码
Patent Pending
国家/地区
美国
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