A Biliverdin-Binding RNA Aptamer for Fluorescent RNAs and a Small RNA Sensor
- Detailed Technology Description
- University of Delawareresearchers have created a fluorescent RNA sensor, which is capable ofdetecting cognate small RNA with high specificity, across a broad dynamicrange. The researchers have also developed a system for screening geneticallyencoded, endogenous fluorophore, biliverdin (BV). The screening andcharacterization of BV-binding RNA aptamers enables non-invasive deep-tissuemonitoring of RNA in vivo. Thetechnology can also be used for measurement of small RNAs or other smallmolecules that can be detected by an RNA-based sensor.
- Countries
- United States
- Application No.
- Patent Pending
- *Abstract
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- *Inquiry
- Denise BierleinLicensing AnalystTelephone: 302-831-4005Email: techtransfer@udel.edu
- *IP Issue Date
- None
- *IP Type
- Provisional
- Country/Region
- USA
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