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Parthenolide

Summary

Parthenolide and its derivatives support the regeneration of peripheral nerve axonal damage.

Technology Benefits

Use of a natural product for the treatment of injured peripheral nerves: Unique mode of action, medical use/compound protection achievable, functional in vivo data from mouse model available
Access to inventor know-how

Technology Application

Peripheral nerve damage repair.

Detailed Technology Description

the natural product parthenolide and its derivatives facilitate the axonal growth and guidance of injured peripheral nerves in cell culture and most significantly also in vivo. The inventors demonstrate that the intraneural injection of parthenolide at the regenerating nerve results in an improved functional motor recovery as well as in an improved sensory functional recovery.

Type of Cooperation

Licensing

Application Date

10/03/2016 00:00:00

Application No.

EP20160709069 20160310

Classes

- international:
A61K31/365; A61P25/28
- cooperative:
A61K31/365; A61K45/06

Others

Patent application

ID No.

4315

Country/Region

Germany

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