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Cure of CLL

Summary

Derivatives of para-nitric oxide-donating acetylsalicylic acid provide novel compounds for the treatment of CLL.

Technology Benefits

Compound claims towards novel derivatives of para-NO-ASA: High selectivity, high activity, tested on different CLL cell populations, proven in a xenograft model of CLL
Development team comprising chemists and clinicians
Compounds may be suitable for the treatment of other neoplasias

Technology Application

effective and selective medicament for the treatment of neoplastic diseases or proliferative disorders

Detailed Technology Description

The present invention provides compounds acting as an effective and selective medicament for the treatment of neoplastic diseases or proliferative disorders, in particular compounds which induce selectively apoptosis of degenerated cells providing reduced side effects in living organisms

Type of Cooperation

Licensing

Application Date

24/09/2014 00:00:00

Application No.

EP20140771921 20140924

Classes

- international:
A61K31/621; A61K31/695; A61P35/00; A61P35/02; C07C203/04; C07C247/10; C07C309/76; C07C69/76; C07F7/08
- cooperative:
A61K31/215; A61K31/235; A61K31/24; A61K31/621; C07C203/04; C07C247/10; C07C309/76; C07C69/75; C07C69/76; C07C69/78; C07C69/86; C07F7/081; C07F7/1804; C07C2601/14

Others

Patent application

ID No.

4045

Country/Region

Germany

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