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RAD51C


Summary

RAD51C as a novel susceptibility gene for hereditary breast and ovarian cancer.


Technology Benefits

RAD51C as a novel susceptibility gene for hereditary: breast cancer, ovarian cancer, head and neck squamous cell carcinomas (HNSCC).
RAD51C as companion diagnostic for PARP or TOPO I Inhibitors.


Technology Application

Professional societies and health care systems, risk-adapted personalized treatment, identify individuals with germline and/or somatic mutation(s) in cancer risk genes


Detailed Technology Description

A novel susceptibility gene for hereditary cancers. RAD51C, which encodes for a protein involved in DNA repair, has been found to be mutated in families with breast and ovarian cancer, but not in healthy control subjects


Type of Cooperation

Licensing


Application Date

09/04/2010 00:00:00


Application No.

EP20100159524 20100409


Classes

- international:
C12Q1/68
- cooperative:
C12Q1/6886; C12Q2600/106; C12Q2600/156


Others

Patent application


ID No.

2301


Country/Region

Germany

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