ProteXadine: Functional Cosmetics for UV Protection and UV Damage Repair

UV Protection and Damage Repair with Anti-aging BenefitsA functional cosmetic portfolio offers UV protection, UV damage repair and anti-aging benefits for the skin. The compounds, ProteXadine, mimic the skin’s natural responses upon exposure to UV light and not only protect DNA from UV damage but also stimulate the body's natural defense mechanisms by activating DNA repair enzymes, the “first steps” of DNA damage repair pathway. In addition, the photoproducts of these compounds are non-toxic.Boosts DNA Repair EnzymesExcessive exposure to the sun increases skin cancer risk and can cause premature aging of the skin, increased epidermal thickness and changes in collagen structure. Current products offer some help, but have several disadvantages. For example, DNA repair cosmetics are generally large molecular weight protein structures known for low stability and poor absorption. Such enzyme-based products do not stimulate production of key repair enzymes. They help only in late-stage repair mechanisms and require expensive formulations to increase efficacy and stability. In addition, active ingredients in most sunscreens absorb light upon UV exposure but can generate very reactive intermediates (free radicals), which can be absorbed by the epidermis and may cause unwanted allergic reactions or sunburns. These new compounds prevent such negative traits by both filtering out damaging UV rays as well as boosting the proportion of key DNA repair enzymes in the skin.BENEFITS AND FEATURES:PhotoprotectionSkin anti-agingNon toxicNatural stimulation of DNA repair enzymesProtects DNA from UV damageSelf-dimerizationUV-B protectionReverse damage and oxidative stress caused by UV exposureMaintains the epidermis and collagen structure and levels in the skinAPPLICATIONS:After sun care productsAnti-aging technologyAnti-wrinkle creamsBathing product linesCosmeticsDNA repair-based treatment formulationsFunctional cosmetic ingredientsCosmeceuticalsMaintenance of epidermal layer and collagen amounts and structureNovel anti-photoaging productsPersonal care productsUV protectionSkin cancer protectionSun cosmeticsSunscreensUV/UV-B absorbersVitiligo, xeroderma pigmentosum, polymorphic light eruption (PMLE) and other hypopigmentation disordersPhase of Development - Animal models, human skin, clinical biochemistry. In vitro studies and in vivo skin studies (mice and human) completed. Safety data available.

USA