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Live Cell Conjugation Chemistry for Imaging, Sensing, Biomanufacturing, and Cell Therapy


Summary

Researchers at Purdue University have developed a new technology that improves the ability to have live cell imaging.  This also allows for biomanufacturing enhancement of cells for therapeutic applications, enhanced killing of cancer cells for cell-drug conjugation, and drug delivery in a pH dependent manner to sites of inflammation.  This technology is used to functionalize small molecules, proteins, florophores, and PET tracers.  It does not use nanoparticles or other vehicles.  This allows for the conjugating cell membranes without killing cells.  This new technology has the potential to change how surface modification of live cells.


Technology Benefits

Functionalized for small molecules, proteins, florophores, and PET tracersNo use of nanoparticles or other vehiclesConjugating cell membranes without killing cells


Technology Application

Cell membrane imagingTherapeutic applications


Detailed Technology Description

Gaurav ChopraChopra Lab


Countries

United States


Application No.

None


Country/Region

USA

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