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Implantable Single-Use Drug Delivery Device for Opioid Overdose


Summary

Researchers from Purdue University have developed an implantable drug delivery device that injects a single dose of naloxone or another anti-opioid overdose drug. The device will inject under the skin of at-risk patients of opioid misuse and activate upon detection of an overdose event. When an overdose occurs, the body reacts with a sudden increase in temperatures and other abrupt changes to normal body function. Such sudden changes trigger the implanted device, allowing the anti-opioid overdose drug to diffuse the overdose before lethal effects occur. The device will facilitate delivery of the antidote for caretakers or emergency responders. In future iterations, incorporating feedback control allows for the automatic release of the antidote upon overdose detection.


Technology Benefits

Facilitates delivery of antidoteEliminates overdoseWirelessImplantable


Technology Application

People at risk for drug overdoseDrug deliveryImplantable devices


Detailed Technology Description

Hyowon LeeLaboratory of Implantable Microsystems ResearchPurdue Biomedical Engineering


Countries

United States


Application No.

None


Country/Region

USA

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