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Using Deferiprone to Target Mitochondrial Iron for the Treatment of Pulmonary Diseases
Detailed Technology Description
This invention discloses the use of the iron chelator, deferiprone for targeting mitochondrial iron as a therapeutic target for IRP2-regulated cigarette smoke-induced bronchitis and emphysema or chronic obstructive pulmonary disease (COPD).
Others
Publication Cloonan S. M., et. al., Mitochondrial ironchelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice.Nature Medicine, 2016.
Country/Region
USA
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