Compositions and Methods of Use for Variant Csy4 Endoribonucleases

Detects as few as a single copy of a target polyribonucleotide

Detect a target nucleotide (e.g., of a pathogen in a biological sample) Purify a particular target RNA (or RNA protein complex) from within a complex mixture  Delivery of modular components (e.g., effector domains) in conjunction with Cas9 Modulate expression of RNA molecules in eukaryotic cells RNA processing enzyme

None

9115348

Related Materials

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

Additional Technologies by these Inventors

• Methods and Compositions for Controlling Gene Expression by RNA Processing
• Structure-Guided Methods Of Cas9-Mediated Genome Engineering
• Methods and Compositions for Using Argonaute to Modify a Single-Stranded Target Nucleic Acid
• Efficient Site-Specific Integration Of New Genetic Information Into Human Cells
• Cas9 Variants With Altered DNA Cleaving Activity
• Split-Cas9 For Regulatable Genome Engineering
• Single-Stranded Nucleic Acid Detection And Imaging System Using Cas9
• Methods For High Signal-To-Noise Imaging Of Chromosomal Loci In Cells Using Fluorescent Cas9
• Identification Of Sites For Internal Insertions Into Cas9
• Cas13a/C2c2 - A Dual Function Programmable RNA Endoribonuclease
• Small Molecule Assisted Cell Penetrating Cas9 RNP Delivery
• THERMOSTABLE RNA-GUIDED ENDONUCLEASES AND METHODS OF USE THEREOF (GeoCas9)
• Cas12c/C2C3 Compositions and Methods of Use
• A Dual-RNA Guided CasZ Gene Editing Technology
• Endoribonucleases For Rna Detection And Analysis

Tech ID/UC Case

19837/2010-028-0

Related Cases

2010-028-0

USA

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